Control of bleeding episodes in patients with blood coagulation factor VIII or factor IX deficiency with inhibitors

Control of bleeding episodes in patients with blood coagulation factor IX deficiency

1. Control of bleeding episodes in patients with blood coagulation factor VIII deficiency
2. Control of bleeding episodes in patients with von Willebrand disease

The following diseases caused by congenital protein C deficiency:

1. Deep vein thrombosis, acute pulmonary thromboembolism
2. Purpuric purpura

Tissue adhesion and closure

1. Hypogammaglobulinemia or agammaglobulinemia
2. Combined use with antibiotics in severe infections
3. Idiopathic thrombocytopenic purpura (when other medications are ineffective and there is a remarkable bleeding tendency and temporary hemostasis management such as surgical treatment or delivery is required)
4. Acute Kawasaki disease (in severe cases with a risk of coronary artery dysfunction)
5. Guillain-Barre syndrome (in severe cases causing difficulties walking in the acute exacerbation phase)
6. Improvement of neuropathy in eosinophilic polyangiitis granulomatosis (only when steroid drugs are ineffective)
7. Chronic inflammatory demyelinating polyneuropathy (including multifocal motor neuropathy (MMN))
8. Acute phase of optic neuritis (in cases where the effect of steroids is insufficient)

1. Hypogammaglobulinemia or agammaglobulinemia
2. Combined use with antibiotics in severe infections

1. Hypoalbuminemia due to loss of albumin (burn injuries, nephrotic syndrome, etc.) and reduced albumin synthesis (liver cirrhosis, etc.)
2. Hemorrhagic shock